Annotation Overview for fig|273036.3.peg.1061 in Staphylococcus aureus RF122:
Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) / Penicillin-binding protein 1A/1B (PBP1)
| current assignment |
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| taxonomy id | 273036 | contig | ||||||
| internal links | genome browser | feature evidence | sequence | ACH [?] | show essentially identical genes | |||||
| annotation history | run tool | |||||||
| data base cross references (dbxref) | ||||||||
This feature is part of a subsystem
Reasons for Current Assignment
The encoded protein plays multiple roles which are implemented by distinct domains within the
feature. The roles are "Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-)"
and "Penicillin-binding protein 1A/1B (PBP1)". The protein occurs in 4 subsystems: "Control of cell
elongation - division cycle in Bacilli", "Methicillin resistance in Staphylococci", "Peptidoglycan
Biosynthesis", and "Type IV pilus". In "Control of cell elongation - division cycle in Bacilli", it
appears to play a functional role that we have not associated with any other gene, and it occurs in
close proximity on the chromosome with 4 other genes from the same subsystem. In "Methicillin
resistance in Staphylococci", it appears to play a functional role that we have not associated with
any other gene. The function of genes having the same functional roles have been described in
Streptococcus pneumoniae (1396576) and Bacillus subtilis (7814321, 9721295). These are homologous proteins which implement the same function.
Compare Regions
The chromosomal region of the focus gene (top) is compared with four similar organisms. The graphic is centered on the focus gene, which is red and numbered 1. Sets of genes with similar sequence are grouped with the same number and color. Genes whose relative position is conserved in at least four other species are functionally coupled and share gray background boxes. The size of the region and the number of genomes may be reset. Click on any arrow in the display to refocus the comparison on that gene. The focus gene always points to the right, even if it is located on the minus strand.
